Mitch McConnell, the most tenured Senate leader in U.S. history, declared his intention Wednesday to relinquish his leadership role come November.

McConnell, who celebrated his 82nd birthday last week, made this announcement from the Senate floor, reflecting on his journey from a newcomer in 1985 to a seasoned leader, the Associated Press reports.

McConnell emphasized the importance of recognizing the right moment to transition to the next phase of life. "One of life's most underappreciated talents is to know when it's time to move on to life's next chapter," he said during his speech.

This decision marks a pivotal shift in the Republican Party, which has been experiencing a profound ideological transformation over the last two decades, moving from the traditional conservatism of Ronald Reagan to the more isolationist and populist approach championed by former President Donald Trump, according to the AP.

Despite his decision to step down as leader, McConnell plans to complete his Senate term, which extends until January 2027. He said his decision was not influenced by health concerns, despite having suffered a concussion from a fall last year and experiencing brief episodes of facial freezing during public speeches.

McConnell's tenure as leader was marked by his strategic acumen, which allowed him to navigate the complex dynamics within the Republican Party, especially in the face of challenges from pro-Trump factions. His leadership was instrumental in key legislative achievements, including significant judicial appointments and tax reforms during Trump's presidency.